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Background: A treatment algorithm and screening examination have been developed to guide patient management and prospectively determine potential for highly active individuals to succeed with nonoperative care after anterior cruciate ligament rupture.

Objective: To prospectively characterize and classify the entire population of highly active individuals over a 10-year period and provide final outcomes for individuals who elected nonoperative care.

Methods: Inclusion criteria included presentation within 7 months of the index injury and an International Knee Documentation Committee level I or II activity level before injury. Concomitant injury, unresolved impairments, and a screening examination were used as criteria to guide management and classify individuals as noncopers (poor potential) or potential copers (good potential) for nonoperative care.

Results: A total of 832 highly active patients with subacute anterior cruciate ligament tears were seen over the 10-year period; 315 had concomitant injuries, 87 had unresolved impairments, and 85 did not participate in the classification algorithm. The remaining 345 patients (216 men, 129 women) participated in the screening examination a mean of 6 weeks after the index injury. There were 199 subjects classified as noncopers and 146 as potential copers. Sixty-three of 88 potential copers successfully returned to preinjury activities without surgery, with 25 of these patients not undergoing anterior cruciate ligament reconstruction at the time of follow-up.

Conclusion: The classification algorithm is an effective tool for prospectively identifying individuals early after anterior cruciate ligament injury who want to pursue nonoperative care or must delay surgical intervention and have good potential to do so.



NAVIGATION


         

 

A tiny filter could have a big impact around the world in the fight against tuberculosis. Using the traditional microscope-based diagnosis method as a starting point, a University of Florida lung disease specialist and colleagues in Brazil have devised a way to detect more cases of the bacterial infection…

 

Up to 30% of the world’s population is infected with Tuberculosis (TB), but in many areas of the world, TB diagnosis still relies on insensitive, poorly standardized, and time-consuming methods. A new diagnostic tool, endorsed by the World Health Organization (WHO), may change that. Dr. Thomas Bodmer shows how it’s done in the Journal of Visualized Experiments (JoVE)…

 

A new study published online in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine shows that from the three TB diagnosis tests commercially available in the U.S., the majority of positives prove to be false positives in populations with a low prevalence of tuberculosis (TB)…

 

A study led by Frank Cobelens of the Amsterdam Institute of Global Health and Development, Amsterdam, The Netherlands and colleagues reports on the cost-effectiveness of implementing the Xpert MTB/RIF diagnostic test for tuberculosis (TB) in high burden countries…

 

The Lancet published a significant development for TB diagnostics yesterday with concrete and encouraging study outcomes on the effectiveness of the new Xpert MTB/RIF test for TB and rifampicin resistance in realistic health care field conditions. One of the authors, Prof. Mark Nicol of the University of Cape Town (South Africa) who contributed to this study, is an EDCTP Senior Fellow…

 

The results of a preliminary study, the work of a research team of the Catholic University, National Institute of Infectious Diseases “L. Spallanzani” and the University of Sassari published in the international journal PLoS One…

 

“The World Health Organization endorsed a new, rapid test for tuberculosis Wednesday that cuts the diagnosis time for patients from months to hours,” CNN reports (Gray, 12/8). Current TB diagnostic tests, which are more than a century old, rely on microscopic examination of a sputum sample and results can take up to three months, the Guardian writes…

 

Scientists at the Health Protection Agency have designed a new test which will identify positive tuberculosis (TB) cases within one hour, according to findings presented at the HPA’s annual conference - Health Protection 2010 - at the University of Warwick today…

 

A tuberculosis test, called Xpert® MTB/RIF, can successfully identify 98% of all culture-confirmed TB cases, including more than 90% of those with smear-negative disease, a study published in NEJM (New England Journal of Medicine) reveals…

 

Research assessing the effectiveness of a new diagnostic test for the detection of tuberculosis (TB) is featured in the Sept. 1 edition of the New England Journal of Medicine…




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