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Background: A treatment algorithm and screening examination have been developed to guide patient management and prospectively determine potential for highly active individuals to succeed with nonoperative care after anterior cruciate ligament rupture.
Objective: To prospectively characterize and classify the entire population of highly active individuals over a 10-year period and provide final outcomes for individuals who elected nonoperative care.
Methods: Inclusion criteria included presentation within 7 months of the index injury and an International Knee Documentation Committee level I or II activity level before injury. Concomitant injury, unresolved impairments, and a screening examination were used as criteria to guide management and classify individuals as noncopers (poor potential) or potential copers (good potential) for nonoperative care.
Results: A total of 832 highly active patients with subacute anterior cruciate ligament tears were seen over the 10-year period; 315 had concomitant injuries, 87 had unresolved impairments, and 85 did not participate in the classification algorithm. The remaining 345 patients (216 men, 129 women) participated in the screening examination a mean of 6 weeks after the index injury. There were 199 subjects classified as noncopers and 146 as potential copers. Sixty-three of 88 potential copers successfully returned to preinjury activities without surgery, with 25 of these patients not undergoing anterior cruciate ligament reconstruction at the time of follow-up.
Conclusion: The classification algorithm is an effective tool for prospectively identifying individuals early after anterior cruciate ligament injury who want to pursue nonoperative care or must delay surgical intervention and have good potential to do so.
NAVIGATION
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20
Apr |
New Optical Technique Promises Rapid And Accurate Diagnosis Of MalariaCategory: Tropical Diseases | Leave a Comment |
Correctly and quickly diagnosing malaria is essential for effective and life-saving treatment. But rapid detection, particularly in remote areas, is not always possible because current methods are time-consuming and require precise instrumentation and highly skilled microscopic analysis…
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11
Apr |
Novel Method To Combat Malaria Drug ResistanceCategory: Tropical Diseases | Leave a Comment |
Researchers from the University of Notre Dame’s Eck Institute for Global Health developed a “gene chip” to contribute to the identification of malaria drug resistance, an effort that will allow for real-time response in modified treatment strategies for this devastating disease. The new discovery is described in a paper appearing in the latest early online edition of the journal Science…
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12
Mar |
Sensors To Test For Malaria And HIV Printed And Assembled For Less Than 10 CentsCategory: Tropical Diseases | Leave a Comment |
Inspired by the paper-folding art of origami, chemists at The University of Texas at Austin have developed a 3-D paper sensor that may be able to test for diseases such as malaria and HIV for less than 10 cents a pop…
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10
Jan |
Ideal New Anti-Malaria Target Revealed In Parasite Protein StructureCategory: Tropical Diseases | Leave a Comment |
Scientists have cracked the structure of a protein that is vital to the parasite Plasmodium falciparum, the one that causes the most deadly form of malaria. They suggest the protein, a key enzyme in the generation of cell membranes, could be an ideal target for anti-malaria drugs, particularly as the protein is not present in humans…
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19
Sep |
African Sleeping Sickness: First Field-Based Molecular Diagnostic Test In SightCategory: Tropical Diseases | Leave a Comment |
The Geneva-based not-for-profit foundation FIND and Japanese diagnostics company Eiken have announced that a next-generation molecular test designed specifically for sleeping sickness - a deadly parasitic disease also known as human African trypanosomiasis (HAT) - is ready to enter accelerated field trials in sites across the Democratic Republic of Congo and Uganda…
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10
Aug |
Tracking Parasite Metabolism Can Uncover Better Drug TargetsCategory: Tropical Diseases | Leave a Comment |
By tracking what parasites eat and detailing the exact pathways down which they metabolize nutrients for growth, researchers in Australia believe they have revealed new drug targets for fighting the deadly tropical parasite Leishmania which infects 12 million and kills half a million people every year…
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Jul |
Preventing Malaria Deaths In The Developing World - With Smelly Socks?Category: Tropical Diseases | Leave a Comment |
Grand Challenges Canada announces a grant today to support further development of a new innovative device to attract and kill mosquitoes that can transmit malaria. Developed by Dr. Fredros Okumu (Ifakara Health Institute, Tanzania), the device is placed outside the home and is the outdoor complement to bed nets and sprays which protect people from infection in their homes…
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14
Jul |
Smelly Socks Help Fight MalariaCategory: Tropical Diseases | Leave a Comment |
The developers of an innovative outdoor decoy device that uses the odour of smelly socks or a similar synthetic smell to lure and kill malaria-carrying mosquitoes, have just won a grant to test their design and then take it from the lab through production to market. Grand Challenges Canada and the Bill & Melinda Gates Foundation have jointly awarded Tanzanian entomologist Dr…
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May |
First Low-Cost And Simple Technology Accurately Diagnoses Malaria In Field Settings Without Blood CollectionCategory: Tropical Diseases | Leave a Comment |
Ben-Gurion University of the Negev researcher Alberto Bilenca, Ph.D., has been awarded a prestigious grant from the Bill & Melinda Gates Foundation to develop a fast, low-cost device to accuracy diagnose malaria without the need for blood collection in field settings…
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Dec |
U.S. Navy’s Project Handclasp Delivers Hydraid® Water Filters To Needy Families Facing Cholera Outbreak In HaitiCategory: Tropical Diseases | Leave a Comment |
Triple Quest, the international distributor of the Hydraid® BioSand water filter, announced the U.S. Navy’s delivery of 150 Hydraid water filters and a fully equipped mobile medical clinic to cholera-stricken Haiti…