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Background: A treatment algorithm and screening examination have been developed to guide patient management and prospectively determine potential for highly active individuals to succeed with nonoperative care after anterior cruciate ligament rupture.
Objective: To prospectively characterize and classify the entire population of highly active individuals over a 10-year period and provide final outcomes for individuals who elected nonoperative care.
Methods: Inclusion criteria included presentation within 7 months of the index injury and an International Knee Documentation Committee level I or II activity level before injury. Concomitant injury, unresolved impairments, and a screening examination were used as criteria to guide management and classify individuals as noncopers (poor potential) or potential copers (good potential) for nonoperative care.
Results: A total of 832 highly active patients with subacute anterior cruciate ligament tears were seen over the 10-year period; 315 had concomitant injuries, 87 had unresolved impairments, and 85 did not participate in the classification algorithm. The remaining 345 patients (216 men, 129 women) participated in the screening examination a mean of 6 weeks after the index injury. There were 199 subjects classified as noncopers and 146 as potential copers. Sixty-three of 88 potential copers successfully returned to preinjury activities without surgery, with 25 of these patients not undergoing anterior cruciate ligament reconstruction at the time of follow-up.
Conclusion: The classification algorithm is an effective tool for prospectively identifying individuals early after anterior cruciate ligament injury who want to pursue nonoperative care or must delay surgical intervention and have good potential to do so.
NAVIGATION
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Dec |
Arteriocyte Announces The Launch Of NANEX™ Stem Cell Expansion System At The Upcoming American Society Of Cell Biology MeetingCategory: Stem Cell Research | Leave a Comment |
Arteriocyte, Inc., a leading clinical stage biotechnology company with offices in Cleveland, Ohio, and Hopkinton, Massachusetts, that develops proprietary stem cell and tissue engineering based therapies announced the launch of its first commercially available Stem Cell Expansion System for research use…
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Nov |
Tests Show Bright Future For Gadonanotubes In Stem Cell TrackingCategory: Stem Cell Research | Leave a Comment |
Gadonanotubes (GNTs) developed at Rice University are beginning to show positive results in a study funded by a federal stimulus grant through the National Institutes of Health (NIH) last year. The study has determined GNTs are effective in helping doctors track stems cells through the body by making them 40 times better than standard contrast agents used in magnetic resonance imaging…
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Jun |
A Launchpad For Stem Cell ResearchCategory: Stem Cell Research | Leave a Comment |
Stem cell research holds promise for improving the quality of human life - especially embryonic stem cells, which can potentially develop into any tissue in the human body. However, basic scientific problems still remain unresolved - but Tel Aviv University researchers are leading the way to inventive solutions…
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Apr |
SRU Biosystems Announces Introduction Of BIND(R) SCANNER For Primary And Stem Cell ApplicationsCategory: Stem Cell Research | Leave a Comment |
SRU Biosystems announced the extension of its product line of label-free instrumentation and biosensors with the introduction of its BIND® SCANNER for primary and stem cell applications. The BIND SCANNER is a first-of-its-kind, plate-based, label-free instrument capable of monitoring cellular responses at an individual cell resolution…
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Feb |
New State-Of-The-Art Technology To Accelerate Stem Cell Research At UC RiversideCategory: Stem Cell Research | Leave a Comment |
Stem cell research at the University of California, Riverside is about to gather speed thanks to the establishment of a new Stem Cell Core Facility (SCCF) - a shared facility providing infrastructure, equipment, and trained personnel for doing stem cell research that ordinarily would not be available in most laboratories…
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Feb |
Translational Regenerative Medicine Forum Sets Stage For Accelerating Therapies To PatientsCategory: Stem Cell Research | Leave a Comment |
The Regenerative Medicine Foundation has announced the first annual Translational Regenerative Medicine Forum to be held April 6-8, 2010 at the Benton Convention Center in Winston-Salem. The forum seeks to advance the field of regenerative medicine and health care innovation through the sharing of scientific discoveries, clinical and corporate best practices and business models…
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Oct |
Celling Technologies Launches The Res-Q Adult Stem Cell Device To Complement Regenerative Medicine PortfolioCategory: Stem Cell Research | Leave a Comment |
Celling Technologies, an innovator in stem cell therapy, launched its latest technology for the isolation of adult stem cells. The Res-Q device was developed by ThermoGenesis Corporation to provide an easy to use, point-of-care system to compliment their MXP system currently being marketed in the United States and several international markets.
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Aug |
The Control Of Living Cells With Light; Advances Could Enhance Stem Cells’ PowerCategory: Stem Cell Research | Leave a Comment |
University of Central Florida researchers have shown for the first time that light energy can gently guide and change the orientation of living cells within lab cultures. That ability to optically steer cells could be a major step in harnessing the healing power of stem cells and guiding them to areas of the body that need help.
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Mar |
Technique May Help Stem Cells Generate Solid Organs, Stanford Study ShowsCategory: Stem Cell Research | Leave a Comment |
Stem cells can thrive in segments of well-vascularized tissue temporarily removed from laboratory animals, say researchers at the Stanford University School of Medicine. Once the cells have nestled into the tissue’s nooks and crannies, the so-called “bioscaffold” can then be seamlessly reconnected to the animal’s circulatory system.
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Jan |
New Device Couples, Fuses Cells For Stem Cell ResearchCategory: Stem Cell Research | Leave a Comment |
MIT engineers have developed a new, highly efficient way to pair up cells so they can be fused together into a hybrid cell. The new technique should make it much easier for scientists to study what happens when two cells are combined. For example, fusing an adult cell and an embryonic stem cell allows researchers to study the genetic reprogramming that occurs in such hybrids.