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Background: A treatment algorithm and screening examination have been developed to guide patient management and prospectively determine potential for highly active individuals to succeed with nonoperative care after anterior cruciate ligament rupture.

Objective: To prospectively characterize and classify the entire population of highly active individuals over a 10-year period and provide final outcomes for individuals who elected nonoperative care.

Methods: Inclusion criteria included presentation within 7 months of the index injury and an International Knee Documentation Committee level I or II activity level before injury. Concomitant injury, unresolved impairments, and a screening examination were used as criteria to guide management and classify individuals as noncopers (poor potential) or potential copers (good potential) for nonoperative care.

Results: A total of 832 highly active patients with subacute anterior cruciate ligament tears were seen over the 10-year period; 315 had concomitant injuries, 87 had unresolved impairments, and 85 did not participate in the classification algorithm. The remaining 345 patients (216 men, 129 women) participated in the screening examination a mean of 6 weeks after the index injury. There were 199 subjects classified as noncopers and 146 as potential copers. Sixty-three of 88 potential copers successfully returned to preinjury activities without surgery, with 25 of these patients not undergoing anterior cruciate ligament reconstruction at the time of follow-up.

Conclusion: The classification algorithm is an effective tool for prospectively identifying individuals early after anterior cruciate ligament injury who want to pursue nonoperative care or must delay surgical intervention and have good potential to do so.



NAVIGATION


         

 

Drug dispensing robots designed to quickly prepare intravenous medications in a sterile environment can harbor dangerous bacteria, according to a report in Infection Control and Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America…

 

454 Life Sciences, a Roche Company (SWX:RO)(SWX:ROG)(Pink Sheets:RHHBY), announced today the launch and immediate availability of the new GS FLX+ System, an instrument capable of generating extra-long sequencing reads up to 1,000 by in length…

 

Oxford Medical Diagnostics (OMD), the developer of breath-based, medical diagnostic technology for the rapid, non-invasive, accurate and low-cost diagnosis and monitoring of metabolic and infectious diseases, today announced it has raised GBP 981,000 in new funding…

 

Covidien (NYSE: COV), a leading global provider of healthcare products, today announced the launch of Conscientious Collaboration, an online resource to promote the importance of ethical and clinically meaningful collaboration between healthcare professionals (HCPs) and the medical device and pharmaceutical industries…

 

The Association for Molecular Pathology (AMP) has released its new position statement on the appropriate manner to reference diagnostic tests in drug labels…

 

The Massachusetts House of Representatives has once again voted to repeal the state’s gift ban, which regulates interactions between physicians and the pharmaceutical industry. The American Medical Student Association (AMSA) urges the Massachusetts Senate to support the ban that clearly translates into better patient care…

 

A pill filled with microscopic, drug-laden adhesive patches is at the center of an agreement between UCSF and Zcube srl, the research corporate venture arm of Italian pharmaceutical leader Zambon Co., SpA, to license UCSF-developed microtechnology and support early research into new ways to deliver oral medications directly to a targeted site in the body…

 

Avantra Biosciences has announced the selection of TGen Drug Development (TD2) as a key test site for Avantra’s new biomarker quantitation platform. Avantra, based near Boston in Woburn, Mass., has created an automated multiplex immunoassay system to evaluate the associations between elevated protein levels, unique patient characteristics, and drug responses…

 

The European medical technology industry association Eucomed restated yesterday its position regarding the upcoming revision of EU medical technology legislation. The industry agrees that the current decentralised system needs to be adapted and improved…

 

The blood test procedure used on newborn infants for 40 years is finding a second life in the search for new lifesaving medications, according to an article in the current edition of Chemical & Engineering News (C&EN), ACS’ weekly newsmagazine…




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