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Background: A treatment algorithm and screening examination have been developed to guide patient management and prospectively determine potential for highly active individuals to succeed with nonoperative care after anterior cruciate ligament rupture.
Objective: To prospectively characterize and classify the entire population of highly active individuals over a 10-year period and provide final outcomes for individuals who elected nonoperative care.
Methods: Inclusion criteria included presentation within 7 months of the index injury and an International Knee Documentation Committee level I or II activity level before injury. Concomitant injury, unresolved impairments, and a screening examination were used as criteria to guide management and classify individuals as noncopers (poor potential) or potential copers (good potential) for nonoperative care.
Results: A total of 832 highly active patients with subacute anterior cruciate ligament tears were seen over the 10-year period; 315 had concomitant injuries, 87 had unresolved impairments, and 85 did not participate in the classification algorithm. The remaining 345 patients (216 men, 129 women) participated in the screening examination a mean of 6 weeks after the index injury. There were 199 subjects classified as noncopers and 146 as potential copers. Sixty-three of 88 potential copers successfully returned to preinjury activities without surgery, with 25 of these patients not undergoing anterior cruciate ligament reconstruction at the time of follow-up.
Conclusion: The classification algorithm is an effective tool for prospectively identifying individuals early after anterior cruciate ligament injury who want to pursue nonoperative care or must delay surgical intervention and have good potential to do so.
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Nov |
Motor Neurone Disease Biomarker Identified By MND Association StudyCategory: Muscular Dystrophy / ALS | Leave a Comment |
A study funded by the Motor Neurone Disease (MND) Association, in collaboration with the Medical Research Council (MRC), has identified a common signature of nerve damage in the brains of MND patients. The study’s exciting findings were published today (2 November 2010) in the prestigious journal Neurology…
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Oct |
Synapse Biomedical Receives FDA Humanitarian Use Device Designation For Amyotrophic Lateral Sclerosis (ALS)Category: Muscular Dystrophy / ALS | Leave a Comment |
Synapse Biomedical Inc. announces that they have received the U.S. Food and Drug Administration (FDA) designation of the NeuRx Diaphragm Pacing System (DPS)™ as a Humanitarian Use Device (HUD) for amyotrophic lateral sclerosis (ALS) patients with a stimulatable diaphragm who are experiencing chronic hypoventilation and has now submitted for Humanitarian Device Exemption (HDE) approval…
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Scientists Unraveling The Causes Of Muscular Dystrophy Awarded $250,000 March Of Dimes PrizeCategory: Muscular Dystrophy / ALS | Leave a Comment |
Two scientists whose work has led to new and better ways to diagnose and potentially treat muscular dystrophy were chosen to receive the 2009 March of Dimes Prize in Developmental Biology. Kevin P. Campbell, Ph.D. and Louis M. Kunkel, Ph.D., will share the 2009 March of Dimes Prize for their pioneering work identifying the genes and proteins that cause muscular dystrophy, a disorder in which the muscles progressively degenerate.