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Background: A treatment algorithm and screening examination have been developed to guide patient management and prospectively determine potential for highly active individuals to succeed with nonoperative care after anterior cruciate ligament rupture.

Objective: To prospectively characterize and classify the entire population of highly active individuals over a 10-year period and provide final outcomes for individuals who elected nonoperative care.

Methods: Inclusion criteria included presentation within 7 months of the index injury and an International Knee Documentation Committee level I or II activity level before injury. Concomitant injury, unresolved impairments, and a screening examination were used as criteria to guide management and classify individuals as noncopers (poor potential) or potential copers (good potential) for nonoperative care.

Results: A total of 832 highly active patients with subacute anterior cruciate ligament tears were seen over the 10-year period; 315 had concomitant injuries, 87 had unresolved impairments, and 85 did not participate in the classification algorithm. The remaining 345 patients (216 men, 129 women) participated in the screening examination a mean of 6 weeks after the index injury. There were 199 subjects classified as noncopers and 146 as potential copers. Sixty-three of 88 potential copers successfully returned to preinjury activities without surgery, with 25 of these patients not undergoing anterior cruciate ligament reconstruction at the time of follow-up.

Conclusion: The classification algorithm is an effective tool for prospectively identifying individuals early after anterior cruciate ligament injury who want to pursue nonoperative care or must delay surgical intervention and have good potential to do so.



NAVIGATION


         

 

A medical device for detecting skin cancer melanoma - MelaFind - has been given an Approvable Letter by the FDA (Food and Drug Administration) in response to its PMA (Pre-Market Approval) application. Mela Sciences says it is liaising with the FDA to finalize patient and physician labeling, as well as providing a user’s guide, and training program…

 

A team of researchers led by scientists at the University of California, San Francisco has developed a way to uncover the evolution of human cancer cells, determining the order in which mutations emerge in them as they wend their way from a normal, healthy state into invasive, malignant masses…

 

Veridex, LLC today announced the launch of the CELLTRACKS® Circulating Melanoma Cell (CMC) kit, providing research scientists with a fast, convenient and reliable way to capture CMCs for research studies…

 

Targeted photodynamic therapy can completely eradicate some models of cancer, according to the latest research by UK and Swiss scientists, published in the current issue of the British Journal of Cancer. The team - including researchers from the University of Hull and ETH Zurich - linked light-sensitive molecules with antibodies that target tumour blood vessels…

 

High-resolution images from a laser-based tool developed at Duke University could help doctors better diagnose melanoma, the deadliest form of skin cancer, while potentially saving thousands of lives and millions of dollars in unnecessary healthcare costs each year…

 

High-resolution images from a laser-based tool developed at Duke University could help doctors better diagnose melanoma, the deadliest form of skin cancer, while potentially saving thousands of lives and millions of dollars in unnecessary healthcare costs each year…

 

The National Institute for Health and Clinical Excellence (NICE) opens consultations on two new medical technology devices: a mattress to prevent inadvertent hypothermia during surgery, and a ´sticking plaster´ used to treat non-melanoma skin cancer…

 

Cascade Technologies, Corp. (OTCBB: CSDT) announced today that, in response to significant recent attention to the Food and Drug Administration (FDA) panel evaluation of Mela Sciences’ (Nasdaq: MELA) MelaFindTM device, the company has received a number of inquiries about its similar instrument. “We believe,” said Dr…

 

MelaFind, a device that helps dermatologists detect suitable samples for skin cancer biopsies has been approved by the General and Plastic Surgery Devices Panel, which advises the FDA (Food and Drug Administration). The vote, 8 in favor and 7 against approving the device, only just got through - there was one abstention…

 

Can skin cancer be treated with light? Scientists at the University of California, Irvine (UC Irvine), believe so…




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