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Background: A treatment algorithm and screening examination have been developed to guide patient management and prospectively determine potential for highly active individuals to succeed with nonoperative care after anterior cruciate ligament rupture.
Objective: To prospectively characterize and classify the entire population of highly active individuals over a 10-year period and provide final outcomes for individuals who elected nonoperative care.
Methods: Inclusion criteria included presentation within 7 months of the index injury and an International Knee Documentation Committee level I or II activity level before injury. Concomitant injury, unresolved impairments, and a screening examination were used as criteria to guide management and classify individuals as noncopers (poor potential) or potential copers (good potential) for nonoperative care.
Results: A total of 832 highly active patients with subacute anterior cruciate ligament tears were seen over the 10-year period; 315 had concomitant injuries, 87 had unresolved impairments, and 85 did not participate in the classification algorithm. The remaining 345 patients (216 men, 129 women) participated in the screening examination a mean of 6 weeks after the index injury. There were 199 subjects classified as noncopers and 146 as potential copers. Sixty-three of 88 potential copers successfully returned to preinjury activities without surgery, with 25 of these patients not undergoing anterior cruciate ligament reconstruction at the time of follow-up.
Conclusion: The classification algorithm is an effective tool for prospectively identifying individuals early after anterior cruciate ligament injury who want to pursue nonoperative care or must delay surgical intervention and have good potential to do so.
NAVIGATION
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22
Feb |
Early Cancer Detection Via New Blood Test: Research In The Early Stages Of Clinical TrialsCategory: Lung Cancer | Leave a Comment |
A simple blood test is being developed by researchers at Ben-Gurion University of the Negev (BGU) and Soroka University Medical Center in Beer-Sheva, Israel that may provide early detection of many types of cancer. Prof. Kapelushnik of BGU’s Faculty of Health Sciences and his team developed a device that illuminates cancer cells with less than a teaspoon of blood…
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Dec |
Lung Cancer Detection From Exhaled BreathCategory: Lung Cancer | Leave a Comment |
Metabolomx, a diagnostic company focused on the detection of the metabolomics signature of cancer from exhaled breath, announces publication of results from the first clinical study demonstrating a breath test that can both detect lung cancer and differentiate between types of lung cancer in humans. This seminal study, conducted at the Cleveland Clinic and led by Dr…
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20
Nov |
New Device Has Potential To Revolutionize Lung Cancer Screening And DiagnosisCategory: Lung Cancer | Leave a Comment |
The metabolism of lung cancer patients is different than the metabolism of healthy people. And so the molecules that make up cancer patients’ exhaled breath are different too. A new device pioneered at the University of Colorado Cancer Center and Nobel-Prize-winning Technion University in Haifa, Israel uses gold nanoparticles to trap and define these molecules in exhaled breath…
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Oct |
Scan Shows High Diagnostic Accuracy For Detection Of Non-Small Cell Lung Cancer MetastasesCategory: Lung Cancer | Leave a Comment |
For patients with non-small cell lung cancer (NSCLC) the accurate determination of the lymph node status before therapy is critical to develop an individualized treatment plan…
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Sep |
Nanotechnology Sensor Could Lead To Earlier Diagnosis For Lung CancerCategory: Lung Cancer | Leave a Comment |
When lung cancer strikes, it often spreads silently into more advanced stages before being detected. In a new article published in Nature Nanotechnology, biological engineers and medical scientists at the University of Missouri reveal how their discovery could provide a much earlier warning signal…
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Jul |
In Non-Small Cell Lung Cancer Patients, TEMLA Shows Higher Diagnostic Yield Than EBUS Or EUS In Largest Reported Series To DateCategory: Lung Cancer | Leave a Comment |
In the largest reported series yet to compare transcervical extended mediastinal lymphadenectomy (TEMLA) with endoscopic and surgical primary staging and restaging of non-small cell lung cancer (NSCLC), TEMLA showed a significantly higher diagnostic yield, according to research presented at the 14th World Conference on Lung Cancer in Amsterdam, hosted by the International Assoc…
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5
Jul |
Utility Of CT Lung Cancer Screening Increased By Adjunctive Use Of 3-D Imaging SystemCategory: Lung Cancer | Leave a Comment |
IASLC presentation addresses key issue from landmark NLST lung cancer study — how to manage high rate of false positive results; lays out protocol for adjunctive use of noninvasive diagnostic test to clarify false positives from CT screening VisionGate, Inc…
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May |
Researchers Are Laying The Foundation For A Future Blood Test For Early Detection Of Lung CancerCategory: Lung Cancer | Leave a Comment |
Scientists working with Professor Dr. Joachim L. Schultze have identified over 480 molecules whose concentration in the blood changes when a person develops lung cancer. These molecules are present in the blood cells either in increased or decreased quantities. “In lung cancer patients, typical patterns which can be detected with a measuring program thus emerge”, explains Prof. Schultze…
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May |
MiRNA Profiling Could Lead To A Blood Test For Lung CancerCategory: Lung Cancer | Leave a Comment |
Researchers have identified characteristic patterns of molecules called microRNA (miRNA) in the blood of people with lung cancer that might reveal both the presence and aggressiveness of the disease, and perhaps who is at risk of developing it. These patterns may be detectable up to two years before the tumor is found by computed tomography (CT) scans…
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13
May |
MiRNA Profiling Could Lead To A Blood Test For Lung CancerCategory: Lung Cancer | Leave a Comment |
Researchers have identified characteristic patterns of molecules called microRNA (miRNA) in the blood of people with lung cancer that might reveal both the presence and aggressiveness of the disease, and perhaps who is at risk of developing it. These patterns may be detectable up to two years before the tumor is found by computed tomography (CT) scans…