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Background: A treatment algorithm and screening examination have been developed to guide patient management and prospectively determine potential for highly active individuals to succeed with nonoperative care after anterior cruciate ligament rupture.

Objective: To prospectively characterize and classify the entire population of highly active individuals over a 10-year period and provide final outcomes for individuals who elected nonoperative care.

Methods: Inclusion criteria included presentation within 7 months of the index injury and an International Knee Documentation Committee level I or II activity level before injury. Concomitant injury, unresolved impairments, and a screening examination were used as criteria to guide management and classify individuals as noncopers (poor potential) or potential copers (good potential) for nonoperative care.

Results: A total of 832 highly active patients with subacute anterior cruciate ligament tears were seen over the 10-year period; 315 had concomitant injuries, 87 had unresolved impairments, and 85 did not participate in the classification algorithm. The remaining 345 patients (216 men, 129 women) participated in the screening examination a mean of 6 weeks after the index injury. There were 199 subjects classified as noncopers and 146 as potential copers. Sixty-three of 88 potential copers successfully returned to preinjury activities without surgery, with 25 of these patients not undergoing anterior cruciate ligament reconstruction at the time of follow-up.

Conclusion: The classification algorithm is an effective tool for prospectively identifying individuals early after anterior cruciate ligament injury who want to pursue nonoperative care or must delay surgical intervention and have good potential to do so.



NAVIGATION


         

 

Oxoid, a world leading microbiology brand, offers a convenient enzyme immunoassay for the rapid and reliable detection of norovirus, the virus responsible for ‘winter vomiting disease’. IDEIA™ Norovirus provides sensitive and specific results in less than 2 hours, allowing outbreaks to be identified quickly and enabling appropriate measures to contain the outbreak to be initiated at the earliest opportunity.

 

A novel, patented mosquito-killing technology developed by U.S. Army researchers under a long-term, joint-development agreement between the Walter Reed Army Institute of Research , the United States Army Medical Research and Materiel Command, and the U.S.

 

Using the Genome Sequencer System from 454 Life Sciences, a Roche company, French scientists have identified a small virus that can actually be parasitic to a larger one. The 50 nm virus, named Sputnik, is associated with a new strain of the giant Acanthamoeba polyphaga mimivirus (APMV) and is believed to represent a currently unknown family of viruses. The study, entitled “The virophage as a unique parasite of the giant mimivirus,” appeared in the September 4th issue of Nature (1).

 

Accelr8 Technology Corporation (Amex: AXK) announced study results today that were presented at the joint sessions of the 48th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) and the Infectious Diseases Society of America (IDSA), October 25-29 in Washington, DC.

 

A probiotic bacterium, Lactobacillus plantarum 299, has been used to out-compete the dangerous bacteria that cause respiratory illness in ventilated patients. Research published in BioMed Central’s open access journal Critical Care describes how applying a bacterial solution in place of normal antiseptics is effective in preventing the most common cause of ventilator-associated pneumonia (VAP).

 

A new University of Colorado at Boulder study indicates that not only do human hands harbor far higher numbers of bacteria species than previously believed, women have a significantly greater diversity of microbes on their palms than men.

 

The American Society for Microbiology (ASM) and the Foundation for Innovative New Diagnostics (FIND) have signed a Memorandum of Understanding confirming their agreement to work in partnership for projects aimed at strengthening infectious disease diagnosis and service integration in resource-poor and transitional countries.




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