The H1N1 flu pandemic in 2009 underscored weaknesses in methods widely used to diagnose the flu, from frequent false negatives to long wait times for results…

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Background: A treatment algorithm and screening examination have been developed to guide patient management and prospectively determine potential for highly active individuals to succeed with nonoperative care after anterior cruciate ligament rupture.
Objective: To prospectively characterize and classify the entire population of highly active individuals over a 10-year period and provide final outcomes for individuals who elected nonoperative care.
Methods: Inclusion criteria included presentation within 7 months of the index injury and an International Knee Documentation Committee level I or II activity level before injury. Concomitant injury, unresolved impairments, and a screening examination were used as criteria to guide management and classify individuals as noncopers (poor potential) or potential copers (good potential) for nonoperative care.
Results: A total of 832 highly active patients with subacute anterior cruciate ligament tears were seen over the 10-year period; 315 had concomitant injuries, 87 had unresolved impairments, and 85 did not participate in the classification algorithm. The remaining 345 patients (216 men, 129 women) participated in the screening examination a mean of 6 weeks after the index injury. There were 199 subjects classified as noncopers and 146 as potential copers. Sixty-three of 88 potential copers successfully returned to preinjury activities without surgery, with 25 of these patients not undergoing anterior cruciate ligament reconstruction at the time of follow-up.
Conclusion: The classification algorithm is an effective tool for prospectively identifying individuals early after anterior cruciate ligament injury who want to pursue nonoperative care or must delay surgical intervention and have good potential to do so.
NAVIGATION
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29
Mar |
Microfluidic Chip Developed To Stem Flu OutbreaksCategory: Flu / Cold / SARS | Leave a Comment |
The H1N1 flu pandemic in 2009 underscored weaknesses in methods widely used to diagnose the flu, from frequent false negatives to long wait times for results…
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2
Mar |
Rapid Flu Tests - How Accurate Are They?Category: Flu / Cold / SARS | Leave a Comment |
Canadian researchers have examined the accuracy of rapid influenza diagnostic tests (RIDTs) in a meta-analysis of 159 studies. The results, published in the Annals of Internal Medicine, revealed that although RIDTs can confirm the flu, they do not rule it out and that RIDTs are also better at identifying the influenza A virus, which is more common, than the influenza B virus…
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28
Feb |
Rapid Influenza Diagnostic Tests Accurate At Diagnosing, But Not Ruling Out The FluCategory: Flu / Cold / SARS | Leave a Comment |
Implementation During Flu Season Could Lead to Earlier Treatment, Better Infection Control According to experts, flu season 2012 is just beginning. Despite the late start, severe flu can be expected to affect up to five million people worldwide. While most patients recover, up to 500,000 will die, with the youngest and oldest being most vulnerable…
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27
Jan |
In Battle To Prevent Pandemic Infection, Clinical Technique Sets New Standard For SpeedCategory: Flu / Cold / SARS | Leave a Comment |
A new diagnosis technique developed by researchers at the RIKEN Omics Science Center (OSC) has succeeded in detecting influenza virus infection in only 40 minutes and with one hundred times the sensitivity of conventional methods…
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5
Aug |
Diagnosing Flu In MinutesCategory: Flu / Cold / SARS | Leave a Comment |
Arriving at a rapid and accurate diagnosis is critical during flu outbreaks, but until now, physicians and public health officials have had to choose between a highly accurate yet time-consuming test or a rapid but error-prone test. A new detection method developed at the University of Georgia and detailed in the August edition of the journal Analyst, however, offers the best of both worlds…
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2
Dec |
FDA Clears Influenza And Respiratory Virus Test Kit From Quest Diagnostics’ Focus Diagnostics BusinessCategory: Flu / Cold / SARS | Leave a Comment |
Quest Diagnostics Incorporated (NYSE: DGX), the world’s leading provider of diagnostic testing, information and services, announced that the U.S. Food and Drug Administration (FDA) has issued 510(k) clearance to the Focus Diagnostics Simplexa Flu A/B & RSV test on the 3M™ Integrated Cycler…
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15
Oct |
Detailing Influenza’s Structure For Drug TargetingCategory: Flu / Cold / SARS | Leave a Comment |
Beating the flu is already tough, but it has become even harder in recent years - the influenza A virus has mutated so that two antiviral drugs don’t slow it down anymore. Reporting their findings in the journal Science, researchers from Florida State and Brigham Young move closer to understanding why not, and how future treatments can defeat the nasty bug no matter how it changes…
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18
Jun |
Researchers Receive 5-Year Grant To Develop Rapid, Robust, User-Friendly Diagnostics For Influenza VirusCategory: Flu / Cold / SARS | Leave a Comment |
An interdisciplinary team of scientists has received a $2.3 million dollar grant from the National Institute for Allergy and Infectious Diseases, one of the National Institutes of Health (NIH). The name of the grant is “Glycan Receptor Mimics for Rapid Detection, Typing, and Susceptibility Testing of Influenza…
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2
Jan |
Rapid Flu Testing System DevelopedCategory: Flu / Cold / SARS | Leave a Comment |
Researchers from the Medical College of Wisconsin, the Children’s Research Institute, and the Children’s Hospital of Wisconsin have developed a rapid, automated system to differentiate strains of influenza…
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1
Jun |
New Device Is A Quicker, Cheaper SARS Virus Detector — One Easily Customizable For Other TargetsCategory: Flu / Cold / SARS | Leave a Comment |
Members of a USC-led research team say they’ve made a big improvement in a new breed of electronic detectors for viruses and other biological materials - one that may be a valuable addition to the battle against epidemics. It consists of a piece of synthetic antibody attached to a nanowire that’s attached to an electrical base, immersed in liquid.