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Background: A treatment algorithm and screening examination have been developed to guide patient management and prospectively determine potential for highly active individuals to succeed with nonoperative care after anterior cruciate ligament rupture.

Objective: To prospectively characterize and classify the entire population of highly active individuals over a 10-year period and provide final outcomes for individuals who elected nonoperative care.

Methods: Inclusion criteria included presentation within 7 months of the index injury and an International Knee Documentation Committee level I or II activity level before injury. Concomitant injury, unresolved impairments, and a screening examination were used as criteria to guide management and classify individuals as noncopers (poor potential) or potential copers (good potential) for nonoperative care.

Results: A total of 832 highly active patients with subacute anterior cruciate ligament tears were seen over the 10-year period; 315 had concomitant injuries, 87 had unresolved impairments, and 85 did not participate in the classification algorithm. The remaining 345 patients (216 men, 129 women) participated in the screening examination a mean of 6 weeks after the index injury. There were 199 subjects classified as noncopers and 146 as potential copers. Sixty-three of 88 potential copers successfully returned to preinjury activities without surgery, with 25 of these patients not undergoing anterior cruciate ligament reconstruction at the time of follow-up.

Conclusion: The classification algorithm is an effective tool for prospectively identifying individuals early after anterior cruciate ligament injury who want to pursue nonoperative care or must delay surgical intervention and have good potential to do so.



NAVIGATION


         

 

A novel system for processing embryos during IVF treatment has been shown to significantly improve the chances of pregnancy - by more than a quarter…

 

Auxogyn, Inc., a privately held medical technology company focused on women’s reproductive health, announced that it initiated a multi-center clinical study to validate its early embryo viability assessment (Eeva™) System for use in in vitro fertilization (IVF)…

 

Home fertility tests may indicate a woman is less fertile than she actually is, according to a study by researchers at the University of North Carolina-Chapel Hill, the Raleigh News & Observer reports. In the study, 100 women older than age 30 who were trying to conceive used home testing kits that claim to gauge a woman’s chances of becoming pregnant…

 

The method used to assess infertility in at-home tests might not be the best for identifying which women will have trouble getting pregnant, according to new research from the University of North Carolina at Chapel Hill School of Medicine…

 

Incept BioSystems, Inc. (”Incept”), a privately-held biomedical device company using patented, microfluidic technology developed at the University of Michigan, announced the completion of the first U.S. human clinical trial of its proprietary, SMART Start™ Embryo Culture System, and the recent submission of a 510(k) application to the U.S. Food & Drug Administration (”FDA”)…

 

Auxogyn, Inc., a privately held medical technology company focused on women’s reproductive health, has announced that it acquired an exclusive license from Stanford University to develop a set of products that may allow medical practitioners in the field of assisted reproduction to significantly improve the effectiveness of in vitro fertilization (IVF) procedures…

 

The Pittsburgh Life Sciences Greenhouse (PLSG), the organization providing capital investments and customized company formation and business growth programs to western Pennsylvania’s life sciences enterprises, announced today that one of its nationally recognized Executives-in-Residence (EIR) has launched a new medical device company; Intimate Bridge to Conception, Inc. (Ib2C(TM))…

 

Researchers at Brown University and Women & Infants Hospital have invented the first artificial human ovary, an advance that provides a potentially powerful new means for conducting fertility research and could also yield infertility treatments for cancer patients. The team has already used the lab-grown organ to mature human eggs…

 

INVO Bioscience, Inc. (OTC Bulletin Board: IVOB), a medical device company focused on treatment options for patients diagnosed with infertility, announced that it has commenced the registration process for its INVOCell fertility device with the State Food and Drug Administration (SFDA) of the Peoples Republic of China (PRC)…

 

In 1989 a 29-year-old Michael Schrader had it all: steady job, a wife, and two wonderful children - daughter Courtney and son Cameron. He couldn’t envision wanting more - that is, more children. Taking steps to keep his nuclear family intact, he underwent vasectomy - a procedure so routine he was back on the golf course the next afternoon…




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