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Background: A treatment algorithm and screening examination have been developed to guide patient management and prospectively determine potential for highly active individuals to succeed with nonoperative care after anterior cruciate ligament rupture.
Objective: To prospectively characterize and classify the entire population of highly active individuals over a 10-year period and provide final outcomes for individuals who elected nonoperative care.
Methods: Inclusion criteria included presentation within 7 months of the index injury and an International Knee Documentation Committee level I or II activity level before injury. Concomitant injury, unresolved impairments, and a screening examination were used as criteria to guide management and classify individuals as noncopers (poor potential) or potential copers (good potential) for nonoperative care.
Results: A total of 832 highly active patients with subacute anterior cruciate ligament tears were seen over the 10-year period; 315 had concomitant injuries, 87 had unresolved impairments, and 85 did not participate in the classification algorithm. The remaining 345 patients (216 men, 129 women) participated in the screening examination a mean of 6 weeks after the index injury. There were 199 subjects classified as noncopers and 146 as potential copers. Sixty-three of 88 potential copers successfully returned to preinjury activities without surgery, with 25 of these patients not undergoing anterior cruciate ligament reconstruction at the time of follow-up.
Conclusion: The classification algorithm is an effective tool for prospectively identifying individuals early after anterior cruciate ligament injury who want to pursue nonoperative care or must delay surgical intervention and have good potential to do so.
NAVIGATION
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29
Aug |
Detection Of Estrogenic Compounds Streamlined By New SensorsCategory: Endocrinology | Leave a Comment |
Researchers have engineered new sensors that fluoresce in the presence of compounds that interact with estrogen receptors in human cells. The sensors detect natural or human-made substances that alter estrogenic signaling in the body. The study appears in the journal Biotechnology and Bioengineering…
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21
Dec |
New Test Shows Promise For Accurate Early Diagnosis Of Turner SyndromeCategory: Endocrinology | Leave a Comment |
A recent study accepted for publication in The Endocrine Society’s Journal of Clinical Endocrinology & Metabolism (JCEM) has demonstrated a novel and accurate test for early diagnosis of Turner syndrome…
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16
Sep |
New Data Suggest Veracyte’s Molecular Test Improves Accuracy Of Thyroid Nodule Diagnosis Using Fine Needle Aspirate (FNA) SamplesCategory: Endocrinology | Leave a Comment |
Veracyte, Inc., a molecular diagnostics company pioneering the emerging field of molecular cytology, announced that initial data from its large-scale, prospective, multi-center clinical trial were presented at the 14th International Thyroid Congress, held in Paris, France…
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29
May |
Novo Nordisk Receives FDA Approval For Norditropin® FlexPro® For Growth Hormone TreatmentCategory: Endocrinology | Leave a Comment |
Novo Nordisk announced that the U.S. Food and Drug Administration (FDA) has approved Norditropin® FlexPro® (somatropin [rDNA origin] injection), a pre-filled injection pen to be used by children and adults with growth hormone disorders. It will be available in the second quarter…
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Jan |
Aneeve To Develop Sensors To Monitor Hormone Levels For Menopause, FertilityCategory: Endocrinology | Leave a Comment |
Aneeve Nanotechnologies LLC has been selected to work in the UCLA on-campus Technology Incubator Program at the California NanoSystems Institute. The startup company will conduct early-stage research for the development of a novel hormone sensor/meter for biomedical applications in the areas of infertility and menopause…
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25
Nov |
Tulane University Surgeon Pioneers ‘Scarless’ Thyroid SurgeryCategory: Endocrinology | Leave a Comment |
Tulane University School of Medicine surgeon Dr. Emad Kandil is one of the first in the country to perform a new form of endoscopic surgery that uses a small incision under the arm to remove all or a portion of the thyroid or parathyroid glands without leaving a scar on the neck. The technique, which was approved by the U.S.
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Nov |
Intravail(R) Drug Delivery Technology Provides Unmatched Non-Invasive Delivery Of An Anti-Obesity PeptideCategory: Endocrinology | Leave a Comment |
Aegis Therapeutics LLC announced today that preclinical data was presented at the 2008 International Congress of Endocrinology in Rio de Janeiro, Brasil demonstrating that its Intravail(R) formulation technology provides unmatched non-invasive delivery of the OB-3 peptide, a peptide previously shown to control weight gain and glucose levels in an animal model of diabetes. The results of the study, presented by Dr.