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Background: A treatment algorithm and screening examination have been developed to guide patient management and prospectively determine potential for highly active individuals to succeed with nonoperative care after anterior cruciate ligament rupture.
Objective: To prospectively characterize and classify the entire population of highly active individuals over a 10-year period and provide final outcomes for individuals who elected nonoperative care.
Methods: Inclusion criteria included presentation within 7 months of the index injury and an International Knee Documentation Committee level I or II activity level before injury. Concomitant injury, unresolved impairments, and a screening examination were used as criteria to guide management and classify individuals as noncopers (poor potential) or potential copers (good potential) for nonoperative care.
Results: A total of 832 highly active patients with subacute anterior cruciate ligament tears were seen over the 10-year period; 315 had concomitant injuries, 87 had unresolved impairments, and 85 did not participate in the classification algorithm. The remaining 345 patients (216 men, 129 women) participated in the screening examination a mean of 6 weeks after the index injury. There were 199 subjects classified as noncopers and 146 as potential copers. Sixty-three of 88 potential copers successfully returned to preinjury activities without surgery, with 25 of these patients not undergoing anterior cruciate ligament reconstruction at the time of follow-up.
Conclusion: The classification algorithm is an effective tool for prospectively identifying individuals early after anterior cruciate ligament injury who want to pursue nonoperative care or must delay surgical intervention and have good potential to do so.
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Feb |
Improved Detection Of Colorectal Cancer By Flexible SigmoidoscopyCategory: Colorectal Cancer | Leave a Comment |
Repeated screening by flexible sigmoidoscopy (FSG) increased the detection of colorectal cancer or advanced adenoma in women by one-fourth and in men by one-third, according to a study published Jan. 31 in the Journal of the National Cancer Institute…
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Dec |
Bowel Cancer Screening Working Up To A Point, Results Of First Million Tests In EnglandCategory: Colorectal Cancer | Leave a Comment |
The NHS bowel cancer screening programme in England is on track to cut bowel cancer deaths by 16%, according to an analysis of the first 1.08 million faecal occult blood tests, but there are concerns that the current method is not picking up diseases as well on the right side of the body as on the left. A paper on the analysis appeared online in the journal Gut on 7 December…
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Oct |
Detecting Pre-Cancerous Colon CellsCategory: Colorectal Cancer | Leave a Comment |
After demonstrating that light accurately detected pre-cancerous cells in the lining of the esophagus, Duke University bioengineers turned their technology to the colon and have achieved similar results in a series of preliminary experiments. This technology could be a non-invasive way for physicians to detect abnormal cells, or dysplasia, which have the potential of turning cancerous…
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Aug |
New Effective And Significantly Less Costly Process May Save Lives Of Lynch Syndrome PatientsCategory: Colorectal Cancer | Leave a Comment |
People who are at risk for a certain form of colon and other types of cancer may soon have a better chance at surviving or even avoiding the diseases, thanks to a new study done by the Intermountain Clinical Genetics Institute at LDS Hospital…
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Aug |
Unresectable Colon Cancer Fuels US Markets For Colonic, Pyloric And Prostatic StentsCategory: Colorectal Cancer | Leave a Comment |
Global Information, Inc. presents a new market research report, “US Markets for Nonvascular Stents 2011″ by Millennium Research Group. A key driver of the growth in colonic and duodenal/pyloric stents will be in the treatment of unresectable colon cancer, which is increasing in incidence and cannot be treated with surgery…
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Jul |
KRAS Diagnostic Test That Assists With Personalized Treatment Of Colorectal Cancer Receives CE MarkCategory: Colorectal Cancer | Leave a Comment |
Roche (SIX: RO, ROG; OTCQX: RHHBY) announced that the cobas KRAS Mutation Test is now commercially available in Europe for use in colorectal cancer. The cobas KRAS Mutation Test identifies mutations in the KRAS gene of colorectal cancer tissue that are predictive of individual response to therapy with anti-epidermal growth factor receptor (EGFR) antibody therapies…
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Apr |
A Less Painful ColonoscopyCategory: Colorectal Cancer | Leave a Comment |
Colonoscopy is regarded as the most thorough way to screen for colon cancer but the potentially life-saving procedure can also be painful. Scientists and engineers are continually researching new methods of screening to reduce patient discomfort while also ensuring the accuracy of the exam…
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Apr |
Nanomedicine Moves One Step Closer To RealityCategory: Colorectal Cancer | Leave a Comment |
A class of engineered nanoparticles - gold-centered spheres smaller than viruses - has been shown safe when administered by two alternative routes in a mouse study led by investigators at the Stanford University School of Medicine…
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Mar |
Bowel Cancer Screening Helping Earlier Detection, UKCategory: Colorectal Cancer | Leave a Comment |
Since a screening programme for bowel cancer was rolled out across England, rates among the target group of over 60s have gone up, showing that screening is helping to detect the UK’s third most common cancer earlier…
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Mar |
New Data In Support Of Link Between Stem Cells And Cancer, Opening Door To New Tools For Diagnosis And TreatmentCategory: Colorectal Cancer | Leave a Comment |
Colorectal cancer cells trigger a set of genes similar to those found in intestinal stem cells, scientists at the Institute for Research in Biomedicine (IRB Barcelona) have found. The team of researchers, led by ICREA researcher Eduard Batlle, propose that patients with colorectal cancer undergo genetic tests of their intestinal epithelium in order to predict a higher risk of relapse…