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Background: A treatment algorithm and screening examination have been developed to guide patient management and prospectively determine potential for highly active individuals to succeed with nonoperative care after anterior cruciate ligament rupture.

Objective: To prospectively characterize and classify the entire population of highly active individuals over a 10-year period and provide final outcomes for individuals who elected nonoperative care.

Methods: Inclusion criteria included presentation within 7 months of the index injury and an International Knee Documentation Committee level I or II activity level before injury. Concomitant injury, unresolved impairments, and a screening examination were used as criteria to guide management and classify individuals as noncopers (poor potential) or potential copers (good potential) for nonoperative care.

Results: A total of 832 highly active patients with subacute anterior cruciate ligament tears were seen over the 10-year period; 315 had concomitant injuries, 87 had unresolved impairments, and 85 did not participate in the classification algorithm. The remaining 345 patients (216 men, 129 women) participated in the screening examination a mean of 6 weeks after the index injury. There were 199 subjects classified as noncopers and 146 as potential copers. Sixty-three of 88 potential copers successfully returned to preinjury activities without surgery, with 25 of these patients not undergoing anterior cruciate ligament reconstruction at the time of follow-up.

Conclusion: The classification algorithm is an effective tool for prospectively identifying individuals early after anterior cruciate ligament injury who want to pursue nonoperative care or must delay surgical intervention and have good potential to do so.



NAVIGATION


         

 

Scientists are reporting refinement of a new test that promises to help assure the safety of supplies of heparin, the blood thinner taken by millions of people worldwide each year to prevent blood clots. The test can quickly and economically detect adulterants, including the substance responsible for hundreds of illnesses and deaths among patients taking heparin in 2008…

 

Sinai Hospital, Northwest Hospital and Levindale Hebrew Geriatric Center and Hospital, LifeBridge Health centers in Baltimore, Md., have begun using the AccuVein AV300, a revolutionary new device that makes drawing blood and inserting IVs a less painful experience for patients…

 

A new blood test is being developed by researchers in Cambridge and Oxford, which, for the first time, could help identify babies at risk of a severe form of sickle cell disease, allowing immediate and more intensive treatment to be given, thanks to a grant from children’s charity Action Medical Research…

 

The University of Alabama at Birmingham has taken a significant step toward making sophisticated cell therapy a part of patient care with its acquisition of the first cell-processing workstation (CPWS) from SANYO North America Corporation (SANYO) in the United States. Richard Marchase, Ph.D…

 

EMIT Corporation announced that it has received U.S. Food and Drug Administration 510(k) clearance to market the HypothermX™ HX100 device…

 

Hospitals can reduce the risk of life-threatening bloodstream infections in children with peripherally inserted central venous catheters by assessing daily the patient’s progress and removing the device as early as possible, according to a new Johns Hopkins Children’s Center study published online March 31 in the journal Clinical Infectious Diseases…

 

A spectrophotometric hemoglobin (SpHb) sensor may become a useful new approach to noninvasive monitoring of blood hemoglobin levels during surgery, reports a study in the April issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS). The SpHb technology could reduce the need for invasive monitoring or the need for blood transfusion during surgery…

 

After three years of exhaustive analysis led by a University of Alberta researcher, the list of known compounds in human blood has exploded from just a handful to more than 4,000. “Right now a medical doctor analyzing the blood of an ailing patient looks at something like 10 to 20 chemicals,” said U of A biochemist David Wishart…

 

A new, rapid blood test that could lead to early diagnosis and potentially save the lives of hundreds of thousands of people stricken with fungal meningitis, a leading cause of AIDS-related deaths in developing countries, is getting closer to market with a recent collaboration between the University of Nevada, Reno and Immuno-Mycologics (IMMY) in Oklahoma…

 

LGC, the international science-based company and market leader in analytical, forensic and diagnostic services and reference standards, is applying its HyBeacons® genotyping technology to Europe’s first-ever large scale trial of pharmacogenetic-guided anticoagulation therapy…




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