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Background: A treatment algorithm and screening examination have been developed to guide patient management and prospectively determine potential for highly active individuals to succeed with nonoperative care after anterior cruciate ligament rupture.
Objective: To prospectively characterize and classify the entire population of highly active individuals over a 10-year period and provide final outcomes for individuals who elected nonoperative care.
Methods: Inclusion criteria included presentation within 7 months of the index injury and an International Knee Documentation Committee level I or II activity level before injury. Concomitant injury, unresolved impairments, and a screening examination were used as criteria to guide management and classify individuals as noncopers (poor potential) or potential copers (good potential) for nonoperative care.
Results: A total of 832 highly active patients with subacute anterior cruciate ligament tears were seen over the 10-year period; 315 had concomitant injuries, 87 had unresolved impairments, and 85 did not participate in the classification algorithm. The remaining 345 patients (216 men, 129 women) participated in the screening examination a mean of 6 weeks after the index injury. There were 199 subjects classified as noncopers and 146 as potential copers. Sixty-three of 88 potential copers successfully returned to preinjury activities without surgery, with 25 of these patients not undergoing anterior cruciate ligament reconstruction at the time of follow-up.
Conclusion: The classification algorithm is an effective tool for prospectively identifying individuals early after anterior cruciate ligament injury who want to pursue nonoperative care or must delay surgical intervention and have good potential to do so.
NAVIGATION
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17
Mar |
Hand Bacteria May One Day Aid Forensic Identification, StudyCategory: Biology / Biochemistry | Leave a Comment |
Next time you leave your computer station or close the lid of your laptop think about this: your mouse and keyboard are covered in hand bacteria that could be traced back to you, according to a new US study that suggests the unique bacterial communities we leave behind on objects we have handled may one day sit alongside DNA and fingerprints as part of the forensic tool…
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13
Feb |
Better Knowledge Of Cell Structure Could Aid Organ Reconstruction, Energy Harvesting, MoreCategory: Biology / Biochemistry | Leave a Comment |
Cornel Sultan, assistant professor of aerospace and ocean engineering at Virginia Tech, is the latest faculty member at the university to learn he has received a National Science Foundation (NSF) Faculty Early Career Development (CAREER) award…
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9
Feb |
Identifying Gene Interactions Through Single-Cell ImagingCategory: Biology / Biochemistry | Leave a Comment |
Cellular imaging offers a wealth of data about how cells respond to stimuli, but harnessing this technique to study biological systems is a daunting challenge…
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3
Feb |
Research At Marshall University May Lead To New Ways To Transport And Manipulate MoleculesCategory: Biology / Biochemistry | Leave a Comment |
A group of Marshall University researchers and their colleagues in Japan are conducting research that may lead to new ways to move or position single molecules - a necessary step if man someday hopes to build molecular machines or other devices capable of working at very small scales. Dr…
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28
Jan |
Ben-Gurion U. Faculty Member Receives 2010 Krill Prize For Scientific ResearchCategory: Biology / Biochemistry | Leave a Comment |
Dr. Anne Bernheim, a senior lecturer at the Department of Chemical Engineering of Ben-Gurion University of the Negev, has been awarded a prestigious Krill Prize for Excellence in Scientific Research 2010. Dr…
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18
Jan |
Latest Techniques For Probing Cellular Dynamics Presented In New Edition Of Popular Lab ManualCategory: Biology / Biochemistry | Leave a Comment |
In recent years, substantial advances have been made in microscopy techniques, enabling biologists to understand the details of cellular structure and dynamics at a level never before possible…
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15
Jan |
Shedding New Light On Early Transmembrane SignalingCategory: Biology / Biochemistry | Leave a Comment |
Two new studies by researchers at the University of Washington further our understanding of the molecular steps in the PLC cascade, a G protein-coupled receptor signaling mechanism that underlies a wide variety of cellular processes, including egg fertilization, hormone secretion, and the regulation of certain potassium channels…
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13
Jan |
Biophysical Society Announces New And Notable Symposium SpeakersCategory: Biology / Biochemistry | Leave a Comment |
The Biophysical Society has announced the speakers for the New and Notable Symposium at the Society’s 54th Annual Meeting in San Francisco, California. The new and notable symposium highlights the latest and most exciting discoveries in biophysics. Speakers are nominated by the Society’s membership and selected by the program committee. Over 150 nominations were received this year…
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13
Jan |
Researchers Synchronize Genetic Clocks In BacteriaCategory: Biology / Biochemistry | Leave a Comment |
Researchers in the US who last year genetically engineered individual bacteria to count time by turning fluorescent proteins inside their cells on and off, have taken their idea a stage further: they have made bacterial colonies of coupled genetic clocks that flash on and off in synchrony, and they have also engineered the bacterial genes so the blinking rate changes …
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12
Dec |
Ending ‘Hit And Miss’ Design In NanomedicineCategory: Biology / Biochemistry | Leave a Comment |
One of the promises of nanomedicine is the design of tiny particles that can home in on diseased cells and get inside them. Nanoparticles can carry drugs into cells and tag cells for MRI and other diagnostic tests; and they may eventually even enter a cell’s nucleus to repair damaged genes. Unfortunately, designing them involves as much luck as engineering…