The tendency of nanoparticles to clump together in solution - “agglomeration” - is of great interest because the size of the clusters plays an important role in the behavior of the materials…
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Background: A treatment algorithm and screening examination have been developed to guide patient management and prospectively determine potential for highly active individuals to succeed with nonoperative care after anterior cruciate ligament rupture.
Objective: To prospectively characterize and classify the entire population of highly active individuals over a 10-year period and provide final outcomes for individuals who elected nonoperative care.
Methods: Inclusion criteria included presentation within 7 months of the index injury and an International Knee Documentation Committee level I or II activity level before injury. Concomitant injury, unresolved impairments, and a screening examination were used as criteria to guide management and classify individuals as noncopers (poor potential) or potential copers (good potential) for nonoperative care.
Results: A total of 832 highly active patients with subacute anterior cruciate ligament tears were seen over the 10-year period; 315 had concomitant injuries, 87 had unresolved impairments, and 85 did not participate in the classification algorithm. The remaining 345 patients (216 men, 129 women) participated in the screening examination a mean of 6 weeks after the index injury. There were 199 subjects classified as noncopers and 146 as potential copers. Sixty-three of 88 potential copers successfully returned to preinjury activities without surgery, with 25 of these patients not undergoing anterior cruciate ligament reconstruction at the time of follow-up.
Conclusion: The classification algorithm is an effective tool for prospectively identifying individuals early after anterior cruciate ligament injury who want to pursue nonoperative care or must delay surgical intervention and have good potential to do so.
NAVIGATION
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28
Oct |
Improved Characterization Of Nanoparticle Clusters For EHS And Biosensors ResearchCategory: Biology / Biochemistry | Leave a Comment |
The tendency of nanoparticles to clump together in solution - “agglomeration” - is of great interest because the size of the clusters plays an important role in the behavior of the materials…
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6
Sep |
Profiler At The Cellular LevelCategory: Biology / Biochemistry | Leave a Comment |
Researchers led by ETH professor Yaakov Benenson and MIT professor Ron Weiss have successfully incorporated a diagnostic biological “computer” network in human cells. This network recognizes certain cancer cells using logic combinations of five cancer-specific molecular factors, triggering cancer cells destruction…
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29
Jul |
New Approaches To Improving Biomarker DiscoveryCategory: Biology / Biochemistry | Leave a Comment |
An article in the current edition of Chemical & Engineering News, ACS’s weekly newsmagazine, describes the trials, tribulations, and triumphs of one of the hottest pursuits in modern biomedical science - the search for “biomarkers” that could greatly improve the diagnosis of disease and efforts to monitor the effectiveness of treatment…
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8
Jul |
Researchers Apply NMR/MRI To Microfluidic ChromatographyCategory: Biology / Biochemistry | Leave a Comment |
By pairing an award-winning remote-detection version of NMR/MRI technology with a unique version of chromatography specifically designed for microfluidic chips, researchers with the U.S…
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29
Jun |
New Method For Imaging Molecules Inside CellsCategory: Biology / Biochemistry | Leave a Comment |
Using a new sample holder, researchers at the University of Gothenburg, Sweden, have further developed a new method for imaging individual cells…
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5
Jun |
Largest Biochemical Circuit Built Out Of Small Synthetic DNA Molecules By Caltech ResearchersCategory: Biology / Biochemistry | Leave a Comment |
In many ways, life is like a computer. An organism’s genome is the software that tells the cellular and molecular machinery - the hardware - what to do. But instead of electronic circuitry, life relies on biochemical circuitry - complex networks of reactions and pathways that enable organisms to function…
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9
May |
Bruker Introduces New Consumable MALDI BiotargetTM For The MALDI BiotyperTM Workflow Using Proteomic Microbial IdentificationCategory: Biology / Biochemistry | Leave a Comment |
At the 21st Annual Meeting of the European Society of Clinical Microbiology and Infectious Diseases, Bruker introduces single-use MALDI BiotargetTM sample plates for the mass spectrometry-based MALDI Biotyper workflow for microbial identification of a wide range of microbial species by means of specific proteomic fingerprints…
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27
Apr |
Diamonds Shine In Quantum NetworksCategory: Biology / Biochemistry | Leave a Comment |
When it comes to dreaming about diamonds, energy efficiency and powerful information processing aren’t normally the thoughts that spring to mind. Unless, of course, you are a quantum physicist looking to create the most secure and powerful networks around…
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1
Apr |
Advanced Cell Diagnostics And Definiens Partner To Develop Tool For Quantitative Biomarker AnalysisCategory: Biology / Biochemistry | Leave a Comment |
Advanced Cell Diagnostics (ACD), a technological leader in molecular pathology, and Definiens, a leading provider for biomedical image and data analysis, announce today a strategic partnership to develop image analysis applications that will enable researchers to accurately quantify specific RNA molecules within individual cells in routine clinical specimen…
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18
Mar |
KTH Royal Institute Of Technology: World Record In DNA AnalysisCategory: Biology / Biochemistry | Leave a Comment |
To date, scientists have been limited to running a small number of DNA samples at a time at a cost of SEK 100,000 per sample. KTH researchers have now come up with a new method which means that 5,000 samples can be run simultaneously for the same price. This cuts the cost per test result considerably and is a world record for the number of samples run in a single DNA sequence analysis…