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Background: A treatment algorithm and screening examination have been developed to guide patient management and prospectively determine potential for highly active individuals to succeed with nonoperative care after anterior cruciate ligament rupture.

Objective: To prospectively characterize and classify the entire population of highly active individuals over a 10-year period and provide final outcomes for individuals who elected nonoperative care.

Methods: Inclusion criteria included presentation within 7 months of the index injury and an International Knee Documentation Committee level I or II activity level before injury. Concomitant injury, unresolved impairments, and a screening examination were used as criteria to guide management and classify individuals as noncopers (poor potential) or potential copers (good potential) for nonoperative care.

Results: A total of 832 highly active patients with subacute anterior cruciate ligament tears were seen over the 10-year period; 315 had concomitant injuries, 87 had unresolved impairments, and 85 did not participate in the classification algorithm. The remaining 345 patients (216 men, 129 women) participated in the screening examination a mean of 6 weeks after the index injury. There were 199 subjects classified as noncopers and 146 as potential copers. Sixty-three of 88 potential copers successfully returned to preinjury activities without surgery, with 25 of these patients not undergoing anterior cruciate ligament reconstruction at the time of follow-up.

Conclusion: The classification algorithm is an effective tool for prospectively identifying individuals early after anterior cruciate ligament injury who want to pursue nonoperative care or must delay surgical intervention and have good potential to do so.



NAVIGATION


         

 

In the days leading up to Glen Deaton’s emergency trip from Trumann to the University of Arkansas for Medical Sciences (UAMS), large veins that drain blood from his brain were clotting. Confusion, nausea, vomiting and blurred vision were among his symptoms. An MRI revealed cerebral venous sinus thrombosis a type of stroke caused by a clot that in Deaton’s case ran from the top of his head nearly to his neck.

 

UCLA researchers have uncovered a new way to scan brain tumors and predict which ones will be shrunk by the drug Avastin - before the patient ever starts treatment. By linking high water movement in tumors to positive drug response, the UCLA team predicted with 70 percent accuracy which patients’ tumors were the least likely to grow six months after therapy. Bronnie McNabb, 57, considers himself lucky.

 

A major clinical challenge is to find the best method to evaluate and to manage the increasing numbers of patients with chronic liver disease. Liver biopsy, due to its risks and limitations, is no longer considered mandatory as the first-line indicator of liver injury, and several markers have been developed as non-invasive alternatives.

 

Scientists in the US have found a way of slowing the growth of ovarian cancer tumors in mice by using nanoparticles to deliver suicide genes to the exact tumor location without damaging healthy cells. They hope a therapy using this method could be tested in humans within the next two years.

 

Scientists in the US have found a way of slowing the growth of ovarian cancer tumors in mice by using nanoparticles to deliver suicide genes to the exact tumor location without damaging healthy cells. They hope a therapy using this method could be tested in humans within the next two years.

 

During 2008, 10% of people who were implanted with the SynCardia temporary CardioWest™ Total Artificial Heart received the device because they were suffering from rejection of their donor heart transplant. Jim Hennigan, 44, received his first heart transplant in 2004 but suffered from rejection of the new heart.

 

Transoma Medical, Inc., manufacturer of Sleuth AT™, the only wireless, automated implantable cardiac monitoring system with programmable and frequent electrocardiogram (ECG) sampling, announced the first patient enrollment and implant in a long-term study to monitor patients who have been prescribed catheter ablation therapy for atrial fibrillation (AF) at risk of recurrence of AF after the procedure. The implant was performed on July 27, 2009, by Dr.

 

Audiologists from America Hears, Inc. now make online house calls to hearing aid customers who install the latest version of the company’s Virtual Office hearing aid programming software on their personal computers at home.

 

(No abstract is available for this citation)

 

(No abstract is available for this citation)




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